Detection of dengue viruses using reverse transcription-loop-mediated isothermal amplification

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Detection of dengue viruses using reverse transcription-loop-mediated isothermal amplification

BACKGROUND Early and rapid detection of dengue virus (DENV) infection during the febrile period is crucial for proper patient management and prevention of disease spread. An easy to perform and highly sensitive method is needed for routine implementation especially in the resource-limited rural healthcare settings where dengue is endemic. METHODS A single-tube reverse transcription-loop-media...

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Colorimetric Detection of Dengue by Single Tube Reverse-Transcription-Loop-Mediated Isothermal Amplification

Dengue is usually diagnosed by isolation of the virus, serology or molecular diagnostic methods. Several commercial kits for the diagnosis of dengue are existing, but concerns have arisen regarding to the affordability and performance characteristics of these kits. Hence, the loop-mediated isothermal amplification (LAMP) is potentially ideal to be used especially in resource limited environment...

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Detection of Raspberry ringspot virus Using Reverse Transcription Loop-mediated Isothermal Amplification

Raspberry ringspot virus (RpRSV), which has not occurred in Japan, infects many plants such as raspberry, gooseberry, cherry, grapevine, and strawberry. Biological assay, enzyme-linked immunosorbent assay (ELISA), and reverse transcription polymerase chain reaction (RT-PCR) have been introduced for the detection of RpRSV in postentry quarantine in Japan. We studied reverse transcription loop-me...

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Accuracy of Reverse Transcription Loop-Mediated Isothermal Amplification Technique for Detecting Dengue Virus

In recent years, researchers have developed a reverse transcription loop-mediated isothermal amplification (RT-LAMP) test as a sensitive and specific technique. But the results of these studies were conflicting. The aim of this meta-analysis was to assess the accuracy of RT-LAMP technique for detecting dengue virus. We systematically searched PUBMED, EMBASE, Web of Science, and the Cochrane Lib...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2013

ISSN: 1471-2334

DOI: 10.1186/1471-2334-13-387